PNAS

A conserved E3 ubiquitin ligase rewires carotenoid, sterol, and lipid metabolism in Xanthophyllomyces dendrorhous

Eukaryotic cells must balance the biosynthesis of sterols, lipids, and in many organisms, carotenoids, which draw on shared acetyl-CoA-derived precursors. Our study identifies the ubiquitin ligase ...
Proceedings of the National Academy of Sciences (PNAS)

Table Of Contents Page, PNAS Volume 123, Number 30

View the Table of Contents for Volume 123, Issue 30 ...
PNAS

Climatic mechanisms underlying a southwestern French Neanderthal refugium at the onset of the last glaciation

Open in Viewer Climatic configuration of the western European margin mid-latitudes during the MIS 5a/4 transition. (Top) Global and Greenland paleoclimatic records compared to the sea surface ...
PNAS

Identification and distribution of a downregulatory signaling alkyloxazole in Streptomyces

Streptomyces use small molecules to dictate morphological development and secondary metabolism. Most of these signaling compounds are inducers derived from γ-butyrolactone (GBL)-synthesizing enzymes.
PNAS

Dietary DNA in municipal wastewater reveals signatures of wealth, immigration, and coastal proximity

Poor diet is a leading driver of chronic disease worldwide, yet current dietary surveillance methods are costly, slow, and prone to bias. We introduce FoodSeq-FLOW (Food Landscape Observation in ...
PNAS

Reducing spread in climate model projections of a September ice-free Arctic

Edited by Mark H. Thiemens, University of California, San Diego, La Jolla, CA, and approved June 14, 2013 (received for review November 13, 2012) The CMIP5 simulations have recently become available ...
PNAS

Motivational trade-offs and modulation of nociception in bumblebees

Insects are traditionally thought to respond to noxious stimuli in an inflexible manner, without the ability to modulate their behavior according to context. We investigated whether bumblebees’ ...
PNAS

On the Riemann Hypothesis in Function-Fields

Note: The article usage is presented with a three- to four-day delay and will update daily once available. Due to ths delay, usage data will not appear immediately following publication. Citation ...
PNAS

Acoustical Impedance and the Theory of Horns and of the Phonograph

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PNAS

EPIGENETIC CONTROL SYSTEMS

Aided by grants from the National Science Foundation. This essay is based on remarks given at a conference on “Extrachromosomal Heredity” held at Gif-sur-Yvette, France, in March, 1958. The conference ...
PNAS

The Influence of Cold in Stimulating the Growth of Plants

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PNAS

Joining the Infra-red and Electric Wave Spectra

Joining the Infra-red and Electric Wave Spectra ...